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1998 1
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2014 3
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2020 5
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53 results

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Page 1
Staphylococcus aureus infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology.
Astrup LB, Skovgaard K, Rasmussen RS, Iburg TM, Agerholm JS, Aalbæk B, Jensen HE, Nielsen OL, Johansen FF, Heegaard PMH, Leifsson PS. Astrup LB, et al. Neurol Res. 2019 May;41(5):399-412. doi: 10.1080/01616412.2019.1573455. Epub 2019 Feb 1. Neurol Res. 2019. PMID: 30707086
CONCLUSIONS: Septic embolic stroke caused brain abscesses, increased mortality and upregulated Orm1 and Cxcl2 gene expressions compared to non-infected embolic stroke. The dramatic Orm1 increase observed in the septic group is unprecedented and suggests a significan …
CONCLUSIONS: Septic embolic stroke caused brain abscesses, increased mortality and upregulated Orm1 and Cxcl2 gene expressions compar …
ORM1 promotes tumor progression of kidney renal clear cell carcinoma (KIRC) through CALR-mediated apoptosis.
Yu G, Gao J, Hu W, Hu D, Wang W, Yang S, Gao J. Yu G, et al. Sci Rep. 2023 Sep 21;13(1):15687. doi: 10.1038/s41598-023-42962-w. Sci Rep. 2023. PMID: 37735575 Free PMC article.
One critical factor is that the mechanism beneath KIRC is unclear. ORM1 is a reactant to acute inflammation. In this study, we demonstrated that methylation of ORM1 promoter was low and ORM1 was expressed significantly higher in KIRC. KIRC with higher …
One critical factor is that the mechanism beneath KIRC is unclear. ORM1 is a reactant to acute inflammation. In this study, we …
Association between epicardial adipose tissue and incident heart failure mediating by alteration of natriuretic peptide and myocardial strain.
Choy M, Huang Y, Peng Y, Liang W, He X, Chen C, Li J, Zhu W, Wei FF, Dong Y, Liu C, Wu Y. Choy M, et al. BMC Med. 2023 Mar 29;21(1):117. doi: 10.1186/s12916-023-02836-4. BMC Med. 2023. PMID: 36978080 Free PMC article.
After fully adjusting, EAT thickness positively correlated with CRP, LEP, GDF15, MMP8, MMP9, ORM1, ANGPTL3, and SERPINE1 and negatively correlated with N-terminal pro-B-type natriuretic peptide (NT-proBNP), IGFBP1, IGFBP2, AGER, CNTN1, and MCAM. ...Mediation effect in the …
After fully adjusting, EAT thickness positively correlated with CRP, LEP, GDF15, MMP8, MMP9, ORM1, ANGPTL3, and SERPINE1 and negative …
Acute phase response, inflammation and metabolic syndrome biomarkers of Libby asbestos exposure.
Shannahan JH, Alzate O, Winnik WM, Andrews D, Schladweiler MC, Ghio AJ, Gavett SH, Kodavanti UP. Shannahan JH, et al. Toxicol Appl Pharmacol. 2012 Apr 15;260(2):105-14. doi: 10.1016/j.taap.2012.02.006. Epub 2012 Feb 16. Toxicol Appl Pharmacol. 2012. PMID: 22366155
In four experiments spanning varied protocols and temporality, healthy (Wistar Kyoto, WKY; and F344) and cardiovascular compromised (CVD) rat models (spontaneously hypertensive, SH; and SH heart failure, SHHF) were intratracheally instilled with saline (control) or LA. Serum biom …
In four experiments spanning varied protocols and temporality, healthy (Wistar Kyoto, WKY; and F344) and cardiovascular compromised (CVD) ra …
Significant changes in ITIH4, AHSG, ORM1, and CD46 content in milk fat globule membrane proteins of ketotic dairy cows.
Gao S, Yang W, Yu H, Liu R, Dong Z, Zhang H, Xia C, Xu C. Gao S, et al. J Dairy Res. 2017 Nov;84(4):407-413. doi: 10.1017/S0022029917000644. J Dairy Res. 2017. PMID: 29154737
We hypothesised that ketosis in postparturient dairy cows would result in altered levels on inflammation-related proteins not only in plasma but also in the milk fat globule membranes (MFGM). ...Blood concentrations of C3, complement C9 (C9), tumour necrosis factor alpha ( …
We hypothesised that ketosis in postparturient dairy cows would result in altered levels on inflammation-related proteins not only in …
S100A proteins as molecular targets in the ocular surface inflammatory diseases.
Tong L, Lan W, Lim RR, Chaurasia SS. Tong L, et al. Ocul Surf. 2014 Jan;12(1):23-31. doi: 10.1016/j.jtos.2013.10.001. Epub 2013 Oct 22. Ocul Surf. 2014. PMID: 24439044 Review.
The S100 proteins are calcium-binding proteins that are exclusively expressed in vertebrates, where they interact with enzymes, cytoskeletal proteins, receptors, transcription factors, and nucleic acids to regulate proliferation, differentiation, apoptosis, inflammation, c …
The S100 proteins are calcium-binding proteins that are exclusively expressed in vertebrates, where they interact with enzymes, cytoskeletal …
Regulation of the amount of ceramide-1-phosphate synthesized in differentiated human podocytes.
Mallela SK, Mitrofanova A, Merscher S, Fornoni A. Mallela SK, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Dec;1864(12):158517. doi: 10.1016/j.bbalip.2019.158517. Epub 2019 Sep 2. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31487557 Free PMC article.
Sphingolipids have important functions as structural components of cells but they also function as signaling molecules regulating different cellular processes such as apoptosis, cell proliferation, cell migration, cell division and inflammation. Hence, a tight regulation o …
Sphingolipids have important functions as structural components of cells but they also function as signaling molecules regulating different …
Orosomucoid 1 Attenuates Doxorubicin-Induced Oxidative Stress and Apoptosis in Cardiomyocytes via Nrf2 Signaling.
Cheng X, Liu D, Xing R, Song H, Tian X, Yan C, Han Y. Cheng X, et al. Biomed Res Int. 2020 Oct 19;2020:5923572. doi: 10.1155/2020/5923572. eCollection 2020. Biomed Res Int. 2020. PMID: 33134382 Free PMC article.
The principal mechanisms of DOX-induced cardiotoxicity are oxidative stress and apoptosis in cardiomyocytes. Orosomucoid 1 (ORM1), an acute-phase protein, plays important roles in inflammation and ischemic stroke; however, the roles and mechanisms of ORM1 in …
The principal mechanisms of DOX-induced cardiotoxicity are oxidative stress and apoptosis in cardiomyocytes. Orosomucoid 1 (ORM1), an …
Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock.
Ruiz-Sanmartín A, Ribas V, Suñol D, Chiscano-Camón L, Palmada C, Bajaña I, Larrosa N, González JJ, Canela N, Ferrer R, Ruiz-Rodríguez JC. Ruiz-Sanmartín A, et al. PLoS One. 2022 Dec 2;17(12):e0278708. doi: 10.1371/journal.pone.0278708. eCollection 2022. PLoS One. 2022. PMID: 36459524 Free PMC article.
Of all of them, and by recursive feature elimination, nine proteins (GPX3, APOB, ORM1, SERPINF1, LYZ, C8A, CD14, APOC3 and C1QC) were associated with organ dysfunction (SOFA > 6) with an accuracy of 0.82 0.06, precision of 0.85 0.093, sensitivity 0.81 0.10, specificity …
Of all of them, and by recursive feature elimination, nine proteins (GPX3, APOB, ORM1, SERPINF1, LYZ, C8A, CD14, APOC3 and C1QC) were …
Plasma and fecal zonulin are not altered by a high green leafy vegetable dietary intervention: secondary analysis of a randomized control crossover trial.
Riviere AJ, Smith KS, Schaberg MN, Greene MW, Frugé AD. Riviere AJ, et al. BMC Gastroenterol. 2022 Apr 12;22(1):184. doi: 10.1186/s12876-022-02248-3. BMC Gastroenterol. 2022. PMID: 35413837 Free PMC article.
BACKGROUND: Zonulin is observed in animal models to regulate intestinal permeability and influenced by dietary intake, gut microbiota, and inflammation. We conducted a secondary analysis of a randomized controlled crossover trial (NCT03582306) in individuals with a BMI gre …
BACKGROUND: Zonulin is observed in animal models to regulate intestinal permeability and influenced by dietary intake, gut microbiota, and …
53 results